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| Episode 1 - [Our First Day Of School] |
| Details : J.D. Turk Cox Kelso and intern Denise return to Sacred Heart to teach med school while new med students Lucy Drew Cole and Maya are put through the ringer on their first day of school. |
| Guest Cast and Crew : Neil Flynn as Concierge | David Kobzantsev as Michael | Antonio Sabàto Jr. as Himself | Robert Maschio as Todd | Sarah Chalke as Elliot Reid | Walter Addison as Ben | Ken Jenkins as Dr. Kelso | Nicky Whelan as Maya | Writer : Bill Lawrence | Director : Michael Spiller | |
| Air Date : Dec. 01, 2009 | Rating ➦ ★★★★★★★ |
| Episode 2 - [Our Drunk Friend] |
| Details : Lucy learns a hard earned lesson about what it takes to be a doctor. Meanwhile J.D. and Turk spot a potential love connection between Denise and the new med student Drew as they play matchmakers with a little bit of help from Dr. Kelso. |
| Guest Cast and Crew : John Billingsley as Alan | Antonio Sabàto Jr. as Himself | Steven Cragg as Lt. Underhill | Windell Middlebrooks as Captain Duncook | Robert Maschio as Todd | Ken Jenkins as Dr. Kelso | Nicky Whelan as Maya | Director : Michael McDonald | Writer : Josh Bycel | Writer : Jonathan Groff | |
| Air Date : Dec. 01, 2009 | Rating ➦ ★★★★★★★ |
| Episode 3 - [Our Role Models] |
| Details : J.D. and Drew learn a tough lesson in mentoring when Dr. Cox and Lucy show them that sometimes the student is the teacher. |
| Guest Cast and Crew : Kurt Doss as Ryan Duncan | Cecelia Antoinette as Mrs. Duncan | Audrey Kearns as Meghan Maroney | Jeremiah Hu as Student | Nicky Whelan as Maya | Director : Gail Mancuso | Writer : Stephen Cragg | |
| Air Date : Dec. 08, 2009 | Rating ➦ ★★★★★★★★ |
| Episode 4 - [Our Histories] |
| Details : While their wives are out of town J.D. and Turk attend a med student's party; Kelso says goodbye to Ted and Gooch. |
| Guest Cast and Crew : Paul Dooley as Paul | Sam Lloyd as Ted | Kate Micucci as Stephanie Gooch | Jim Hazelton as David Izzle | Windell Middlebrooks as Captain Duncook | Nicky Whelan as Maya | Director : Ken Whittingham | Writer : Corey Nickerson | |
| Air Date : Dec. 15, 2009 | Rating ➦ ★★★★★★ |
| Episode 5 - [Our Mysteries] |
| Details : J.D. still clamors for Dr. Turk's approval as he approaches his final day of teaching at Sacred Heart Lucy searches within herself for the courage to perform a basic medical procedure on a real human and Denise and Drew make things official. |
| Guest Cast and Crew : Sonal Shah as Sunny Day | Ken Jenkins as Dr. Kelso | Nicky Whelan as Maya | Matthew Moy as Trang | Director : Michael Spiller | Writer : Steven Cragg | |
| Air Date : Dec. 22, 2009 | Rating ➦ ★★★★★★ |
| Episode 6 - [Our New Girl-Bro] |
| Details : While Turk struggles to find a replacement best friend Elliott offers some sound advice and guidance to an over-worked and exhausted Lucy. |
| Guest Cast and Crew : Windell Middlebrooks as Capt. Duncook | Gary Ballard as Mr. Biegel | Betty A. Bridges as Ms. Simmons | Robert Maschio as Todd | Sarah Chalke as Elliot Reid | Ken Jenkins as Dr. Kelso | Matthew Moy as Trang | Writer : Kevin Etten | Director : Michael McDonald | |
| Air Date : Jan. 01, 2010 | Rating ➦ ★★★★★★ |
| Episode 7 - [Our White Coats] |
| Details : Before receiving their white coats the med students of Winston University must figure out why they want to be doctors and Denise gets a little relationship help from Elliot. |
| Guest Cast and Crew : Gary Ballard as Kevin Biegel | David Cade as Boots | John Lanz as Eric Puritsky | Elliot Schwartz as Roger | Tony Tambi as Joseph | Dan Sachoff as Professor | Windell Middlebrooks as Captain Duncook | Robert Maschio as Todd | Sarah Chalke as Elliot Reid | Ken Jenkins as Dr. Kelso | Director : John Putch | Writer : Andy Schwartz | |
| Air Date : Jan. 05, 2010 | Rating ➦ ★★★★★★★ |
| Episode 8 - [Our Couples] |
| Details : Lucy finds couplings dysfunctional or not throughout the hospital |
| Guest Cast and Crew : Tony Tambi as Joseph | Windell Middlebrooks as Captain Duncook | Tom Ormeny as Arthur | Logan Fields as Kid | Robert Maschio as Todd | Geoff Stevenson as Dr. Beardfacé | Nicky Whelan as Maya | Matthew Moy as Trang | Director : Chris Koch | Writer : Prentice Penny | |
| Air Date : Jan. 05, 2010 | Rating ➦ ★★★★★★ |
| Episode 9 - [Our Stuff Gets Real] |
| Details : The reality of having a baby begins to settle in for both J.D. and Elliot while Lucy struggles with the reality of operating on people. |
| Guest Cast and Crew : Edith Fields as Mrs. Foster | Robert Maschio as Todd | Sarah Chalke as Elliot Reid | Walter Addison as Ben | Art Frankel as Mr. Foster | Christa Miller as Jordan Sullivan | Director : John Putch | Writer : Leila Strachan | |
| Air Date : Jan. 12, 2010 | Rating ➦ ★★★★★★★ |
| Episode 10 - [Our True Lies] |
| Details : A case of guilty conscience plagues the med school when a student cheats on an exam and Dr. Cox takes it out on the entire class. Meanwhile Denise makes a startling admission of her own. |
| Guest Cast and Crew : Nadine Velázquez as Nicole | Robert Maschio as Todd | Tracy McCubbin as Nurse Sheila | Ginna Rutter as 75-Year Old Lucy | Ken Jenkins as Dr. Kelso | Nicky Whelan as Maya | Matthew Moy as Trang | Director : Michael Spiller | Writer : Danny Rubin | Writer : Lon Zimmet | |
| Air Date : Jan. 19, 2010 | Rating ➦ ★★★★★★★ |
| Episode 11 - [Our Dear Leaders] |
| Details : Lucy takes her new assignment as hell week team leader a bit too seriously and Dr. Turk feels threatened when an internationally renowned surgeon pays a visit. |
| Guest Cast and Crew : Reno Wilson as Russell Vaughn | Robert Maschio as Todd | Judy Kain as Irene Kelly | Ken Jenkins as Dr. Kelso | Nicky Whelan as Maya | Matthew Moy as Trang | Director : Peter Lauer | Writer : Kevin Etten | Writer : Corey Nickerson | |
| Air Date : Jan. 26, 2010 | Rating ➦ ★★★★★★★ |
| Episode 12 - [Our Driving Issues] |
| Details : When Cole and Kelso both get negative results back after a few routine tests they learn the hard way to put their egos in check in order to rein in the support of their so-called friends. |
| Guest Cast and Crew : Jane Le as Ming | Ken Jenkins as Dr. Kelso | Matthew Cardarople as Frank | Nicky Whelan as Maya | Matthew Moy as Trang | Director : Eren Celeboglu | Writer : Prentice Penny | Writer : Alessia Costantini | |
| Air Date : Mar. 10, 2010 | Rating ➦ ★★★★★★ |
| Episode 13 - [Our Thanks] |
| Details : The med students of Winston University finally find something to be thankful for when Cole identifies his true calling in surgery Drew finds the love of his life and Lucy finds the inspiration to become a doctor. |
| Guest Cast and Crew : Larry Sullivan as Eric Coleman | Robert Maschio as Todd | Nicky Whelan as Maya | Ryan Biegel as Clint | Matthew Moy as Trang | Director : Rick Blue | Writer : Sean Russell | |
| Air Date : Mar. 17, 2010 |